Can NOW Supplements Curcumin Phytosome Bio-Enhanced Turmeric Extract Help with High Cholesterol?
Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 14 Researches
8.5
USERS' SCORE
Good
Based on 9 Reviews
8.6
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Curcumin Phytosome(Turmeric Rhizome Extract (curcuma longa)/Phosphatidyl Choline Complex) (Meriva® Turmeric Phytosome)(Standardized to min. 18% Curcuminoids - 90 mg)
500 mg
**
Top Medical Research Studies
8
Turmeric improves cholesterol levels
Effects of curcumin/turmeric supplementation on lipid profile: A GRADE-assessed systematic review and dose-response meta-analysis of randomized controlled trials.
We aimed to understand how turmeric, specifically its active compound curcumin, affects cholesterol levels in the body. After searching several online databases and analyzing 64 randomized clinical trials, we found that turmeric supplementation can lead to noticeable improvements in key cholesterol metrics.
Specifically, we observed significant reductions in total cholesterol, triglycerides, and low-density lipoprotein cholesterol (often referred to as "bad" cholesterol). Additionally, there was an increase in high-density lipoprotein cholesterol, known as "good" cholesterol. However, it's important to note that turmeric did not show considerable effects on related apolipoproteins, which are proteins that help carry cholesterol in the blood.
Although these results are promising, we must approach them with caution. The quality of evidence was assessed to be low and very low regarding these outcomes. This means that while turmeric supplementation does seem to help with certain cholesterol levels, more rigorous studies are needed to confirm these benefits and properly evaluate the overall efficacy.
Read More
9
Curcumin improves cholesterol levels
The Effect of Curcumin on Reducing Atherogenic Risks in Obese Patients with Type 2 Diabetes: A Randomized Controlled Trial.
We conducted a randomized, double-blind, placebo-controlled trial to understand how curcumin, a compound found in turmeric, might help in reducing high cholesterol levels in obese patients with type 2 diabetes.
Our study included 227 participants and focused on various key measurements, such as pulse wave velocity and cholesterol levels, specifically looking at low-density lipoprotein (LDL) cholesterol, known for its connection to heart health.
Over a 12-month period, those who took curcumin showed significant improvements. We noticed a remarkable reduction in pulse wave velocity, which is crucial for assessing cardiovascular risk. Additionally, levels of harmful LDL cholesterol and other cardiometabolic markers were also significantly lower in the curcumin group.
These positive findings suggest that turmeric’s active ingredient, curcumin, could be an effective natural option for managing atherogenic risks, particularly in individuals battling both obesity and diabetes.
We examined the impact of Curcuma wenyujin, commonly known as turmeric, on cholesterol levels and fat accumulation in the body. In our research, we focused on the extract from turmeric rhizomes and its effects on both cells in a lab setting and mice with high-fat diets. We observed a notable decrease in lipid accumulation in liver cells treated with the extract.
Specifically, the petroleum ether fraction of turmeric extract significantly lowered total cholesterol levels in the liver and bloodstream, alongside a reduction in liver fat. Interestingly, this was achieved without changing the food intake of the mice involved in the study. Moreover, we noted improvements in liver enzymes that are often elevated with poor fat metabolism.
Our findings also indicated that turmeric enhances fat breakdown and boosts the body’s natural cleaning process, known as autophagy, which helps remove excess fats. With 21 identified beneficial compounds within the extract, particularly sesquiterpenes, turmeric seems to offer a promising approach to managing high cholesterol and improving overall metabolic health.
Read More
Most Useful Reviews
9
Metabolic syndrome support
110 people found this helpful
Curcumin lowers bad cholesterol, slows blood clot formation, and blocks inflammatory substances. Turmeric is excellent for reducing metabolic syndrome and preventing atherosclerosis.
Read More
9
Knee pain relief
2 people found this helpful
I purchased this for my mother to normalise her cholesterol levels and reduce inflammation. It has significantly helped, as her knee pain has diminished and her elbow bruise has also improved.
Read More
9
Heart health improvement
1 people found this helpful
My natural health physician advises that turmeric is remarkable for its anti-inflammatory properties. It can lower high cholesterol and improve heart health. This product is easily absorbed and has become a crucial supplement for my husband and me.
We analyzed the effects of turmeric on high cholesterol by conducting a study involving 30 patients. Half of the participants received a traditional fat-soluble Curcumin extract paired with piperine, while the other half took a water-soluble form known as Curcuin. Both groups were monitored for their levels of inflammation and cholesterol over a period of 90 days.
After this duration, we observed that both turmeric extracts led to a reduction in key inflammatory markers like Erythrocyte Sedimentation Rate (ESR) and C-reactive protein (CRP), as well as a decrease in cholesterol levels. Participants consuming the water-soluble Curcuin showed even more significant improvements compared to those taking the traditional extract.
Our findings suggest that turmeric may be a valuable addition to dietary strategies aimed at managing inflammation and lowering cholesterol levels. However, we also noted that the group taking the fat-soluble Curcumin combined with piperine exhibited beneficial effects, raising questions about dosage forms and frequencies for optimal results. Further studies are required to fine-tune these parameters and better understand how best to use turmeric for health benefits.
Read More
9
Turmeric improves cholesterol levels
Synergistic Effects of Turmeric, Strawberry and Broccoli in Improving Lipid Profile in Adult Patients with Hypercholesterolemia.
We explored the effects of turmeric combined with strawberries and broccoli on cholesterol levels in adults facing hypercholesterolemia. The study involved twenty participants who consumed 600 mg of turmeric daily, along with 100 grams each of fresh strawberries and boiled broccoli for a month.
At the beginning of the study, we measured various health indicators, including cholesterol levels. For total cholesterol, we observed a decrease from 239.75 mg/dL to 220.7 mg/dL, which is statistically significant. Similarly, LDL cholesterol, known as the "bad" cholesterol, dropped from 172.9 mg/dL to 153.95 mg/dL, and triglycerides saw a decline from 193.7 mg/dL to 145 mg/dL after the treatment. However, while HDL cholesterol, often referred to as the "good" cholesterol, decreased slightly, we still found it meaningful that the overall lipid profile improved significantly with this combination of foods.
Beyond cholesterol, other blood parameters remained normal throughout the study, suggesting the treatment was safe and well-tolerated. In summary, incorporating turmeric, strawberries, and broccoli into the diet appears beneficial for lowering cholesterol levels, contributing to healthier lipid profiles for those with hypercholesterolemia.
Read More
9
Curcumin improves cholesterol levels
The Effect of Curcumin on Reducing Atherogenic Risks in Obese Patients with Type 2 Diabetes: A Randomized Controlled Trial.
We conducted a randomized, double-blind, placebo-controlled trial to understand how curcumin, a compound found in turmeric, might help in reducing high cholesterol levels in obese patients with type 2 diabetes.
Our study included 227 participants and focused on various key measurements, such as pulse wave velocity and cholesterol levels, specifically looking at low-density lipoprotein (LDL) cholesterol, known for its connection to heart health.
Over a 12-month period, those who took curcumin showed significant improvements. We noticed a remarkable reduction in pulse wave velocity, which is crucial for assessing cardiovascular risk. Additionally, levels of harmful LDL cholesterol and other cardiometabolic markers were also significantly lower in the curcumin group.
These positive findings suggest that turmeric’s active ingredient, curcumin, could be an effective natural option for managing atherogenic risks, particularly in individuals battling both obesity and diabetes.
We examined the impact of Curcuma wenyujin, commonly known as turmeric, on cholesterol levels and fat accumulation in the body. In our research, we focused on the extract from turmeric rhizomes and its effects on both cells in a lab setting and mice with high-fat diets. We observed a notable decrease in lipid accumulation in liver cells treated with the extract.
Specifically, the petroleum ether fraction of turmeric extract significantly lowered total cholesterol levels in the liver and bloodstream, alongside a reduction in liver fat. Interestingly, this was achieved without changing the food intake of the mice involved in the study. Moreover, we noted improvements in liver enzymes that are often elevated with poor fat metabolism.
Our findings also indicated that turmeric enhances fat breakdown and boosts the body’s natural cleaning process, known as autophagy, which helps remove excess fats. With 21 identified beneficial compounds within the extract, particularly sesquiterpenes, turmeric seems to offer a promising approach to managing high cholesterol and improving overall metabolic health.
Read More
9
Curcumin nicotinate lowers cholesterol
Curcumin nicotinate increases LDL cholesterol uptake in hepatocytes through IDOL/LDL-R pathway regulation.
We explored the effects of curcumin nicotinate, a compound derived from turmeric and niacin, on cholesterol levels. Our study focused on its ability to enhance the regulation of the LDL cholesterol receptor pathway in liver cells, which is crucial for lowering bad cholesterol levels in the body.
Using a series of experiments, including metabolite profiling and molecular docking studies, we discovered that curcumin nicotinate significantly influences lipid metabolism. In tests involving liver cells, we observed that it improved the uptake of LDL cholesterol and increased the expression of LDL receptors. Furthermore, in an animal model with Wistar rats fed a high-fat diet, curcumin nicotinate demonstrated a reduction in liver cholesterol levels.
These findings suggest that curcumin nicotinate could play a role in managing high cholesterol, likely due to its interaction with the IDOL/LDLR pathway, alongside its known effects on another protein called PCSK9. Overall, curcumin nicotinate emerges as a promising candidate for treating hyperlipidemia and promoting heart health through its natural ingredients.
Curcumin lowers bad cholesterol, slows blood clot formation, and blocks inflammatory substances. Turmeric is excellent for reducing metabolic syndrome and preventing atherosclerosis.
Read More
9
Knee pain relief
2 people found this helpful
I purchased this for my mother to normalise her cholesterol levels and reduce inflammation. It has significantly helped, as her knee pain has diminished and her elbow bruise has also improved.
Read More
9
Heart health improvement
1 people found this helpful
My natural health physician advises that turmeric is remarkable for its anti-inflammatory properties. It can lower high cholesterol and improve heart health. This product is easily absorbed and has become a crucial supplement for my husband and me.
Read More
9
Women's health benefit
This product is of good quality and beneficial for women's health. Curcumin acts as a potent antioxidant, improving the immune system by fighting cell-damaging free radicals more effectively than Vitamin C.
Read More
8
Lowered cholesterol levels
2 people found this helpful
Highly recommended! This supplement has helped reduce my high cholesterol levels. Since I started taking a daily capsule, my test results have shown a decrease. I appreciate the dark capsules, as they maintain quality better.
High cholesterol, or hyperlipidemia, is a medical condition characterized by an elevated level of cholesterol in the bloodstream. Cholesterol is a waxy, fat-like substance that’s essential for building healthy cells, but too much of it can lead to serious health issues, including heart disease and stroke. Cholesterol is carried through the blood by lipoproteins, with two main types being low-density lipoprotein (LDL) and high-density lipoprotein (HDL). LDL, often referred to as "bad" cholesterol, can lead to the buildup of plaque in the arteries, while HDL, known as "good" cholesterol, helps carry cholesterol away from the arteries and back to the liver.
Factors contributing to high cholesterol can include poor diet, lack of exercise, obesity, smoking, and genetic predisposition. Regular health screenings are crucial, as high cholesterol often presents no overt symptoms. Maintaining a heart-healthy diet rich in fruits, vegetables, whole grains, and healthy fats, coupled with regular physical activity and avoiding tobacco, can help manage cholesterol levels effectively. In some cases, medications may be necessary to control high cholesterol, so consulting with a healthcare provider is key for tailored advice.
Turmeric curcumin is a natural compound derived from the root of the turmeric plant (Curcuma longa), a spice commonly used in cooking, particularly within Indian cuisine. Curcumin is the primary active ingredient in turmeric, known for its bright yellow color and various health benefits. It boasts strong anti-inflammatory and antioxidant properties, which have made it popular in both culinary practices and dietary supplements. Many people incorporate turmeric curcumin into their diets in order to support overall health, alleviate joint pain, and bolster immune function.
In recent years, turmeric curcumin has gained attention in the wellness community, leading to the production of numerous supplements that isolate this powerful compound. When considering turmeric curcumin supplements, it's essential to note that curcumin is poorly absorbed by the body on its own, so many products include added black pepper extract (piperine) to enhance absorption. As the potential health benefits and culinary uses of turmeric curcumin continue to be explored, a growing number of consumers are incorporating it into their lifestyles for its perceived benefits. However, as with any supplement, it's advisable to consult with a healthcare professional before starting a new regimen.
Turmeric, specifically its active component curcumin, has been the subject of various studies examining its potential health benefits, including its effect on cholesterol levels. Some research suggests that curcumin may help improve lipid profiles by decreasing total cholesterol and LDL (low-density lipoprotein) cholesterol, often referred to as "bad" cholesterol, while potentially raising HDL (high-density lipoprotein) cholesterol—known as "good" cholesterol. The anti-inflammatory and antioxidant properties of curcumin are believed to play a role in these beneficial effects.
However, while the preliminary findings are promising, it’s essential to approach curcumin supplementation with caution. Many studies utilize higher doses than what is typically found in culinary use, and further research is needed to establish effective doses and long-term effects. Always consult with a healthcare professional before starting any new supplement, especially if you are currently managing cholesterol levels or have underlying health conditions. Additionally, turmeric and curcumin should not replace prescribed cholesterol medications but rather be considered as a complementary approach to heart health.
Based on user reviews, many individuals have reported observing results from taking curcumin supplements for high cholesterol in a relatively short timeframe. For instance, one user indicated that after starting a daily regimen, they noticed a reduction in their cholesterol levels confirmed by test results. This suggests that effects can often be seen quite quickly, potentially within a few weeks of consistent use Read Review.
Additionally, another user mentioned significant improvements in their mother’s cholesterol levels and inflammation, again emphasizing a positive effect from this supplement. While specific timeframes may vary among users, many highlight the importance of following the recommended dosage to achieve noticeable results, particularly with curcumin’s high bioavailability contributing to its effectiveness Read Review.
Curcumin, the key compound in turmeric, has garnered attention in scientific research for its potential benefits in managing high cholesterol levels. A comprehensive umbrella review of systematic reviews and meta-analyses involving randomized controlled trials highlighted that curcumin exhibits significant anti-lipidemic effects, particularly in individuals with noncommunicable diseases [1]. Furthermore, various studies have demonstrated that curcumin supplementation can lead to reductions in total cholesterol, LDL cholesterol (the "bad" cholesterol), and triglycerides, while sometimes increasing HDL cholesterol (the "good" cholesterol) [14].
In specific populations, such as women with polycystic ovary syndrome (PCOS), curcumin supplementation has shown promising results, indicating a notable decrease in total cholesterol levels [2]. In animal studies, curcumin has been effective in managing cholesterol levels and reducing fat accumulation [3], while other studies have linked its benefits to improved cardiovascular health and decreased inflammation [11]. Overall, the evidence suggests that curcumin could be a beneficial supplement for individuals looking to manage high cholesterol, especially when considering its incorporation into a broader lifestyle strategy that fosters cardiovascular health.
Based on user reviews, many individuals have reported notable improvements in a variety of symptoms attributed to curcumin supplements. For instance, several users pointed out that curcumin effectively lowers bad cholesterol levels, with one user specifically stating that their test results confirmed a decrease after consistent use of the supplement Read Review. Additionally, users have shared experiences of reduced inflammation and joint pain, with one review mentioning significant alleviation of knee pain and bruising Read Review.
Moreover, several users emphasized the supplement's antioxidant properties, noting improvements in their overall immune function and health benefits, particularly for conditions like arthritis Read Review. While the timeline for experiencing these benefits can vary among individuals, many users recommend following the recommended dosage to achieve optimal results, further stressing curcumin's higher bioavailability as a significant factor in its effectiveness Read Review. Overall, anecdotal evidence suggests that users have found curcumin to be a beneficial addition to their health routines, though individual outcomes may differ.
Users have reported positive experiences when combining curcumin supplements with other health routines aimed at managing high cholesterol. Many reviewers, like the one who mentioned their mother's improved cholesterol levels, suggest that curcumin can complement other treatments by addressing not only cholesterol concerns but also inflammation and joint pain Read Review. Reviewers also note that professionals endorse the supplement for its notable anti-inflammatory properties and overall heart health benefits, which suggests that it may enhance the effectiveness of other cholesterol-lowering strategies Read Review.
Additionally, users highlighted curcumin's high bioavailability and antioxidant capabilities, which help improve immune function and potentially work in tandem with other supplements or medications Read Review. The consensus among users is that while curcumin can be taken on its own, its benefits may be amplified when incorporated into a broader health regimen aimed at managing cholesterol levels and promoting overall heart health Read Review.
Research indicates that a dosage of 600 mg of turmeric daily may be optimal for lowering cholesterol levels, particularly when combined with other foods like strawberries and broccoli. In a study involving twenty participants, this combination led to a significant reduction in total cholesterol and LDL ("bad") cholesterol levels over a month, improving their lipid profiles markedly [5].
Additionally, other studies have also demonstrated that curcumin, the active compound in turmeric, can help improve cholesterol metrics when taken consistently over time, ideally for at least eight weeks [1]. Those focusing on specific populations, such as women with PCOS or obese individuals, also saw significant benefits from curcumin supplementation in managing cholesterol levels [2][7]. However, it's crucial to consider that formulations with higher bioavailability, or combinations with other compounds like piperine, may enhance the effects of turmeric on cholesterol management [4]. Overall, integrating turmeric into a balanced diet appears beneficial, but the best approach may vary based on individual health circumstances.
8
Lowered cholesterol levels
2 people found this helpful
Highly recommended! This supplement has helped reduce my high cholesterol levels. Since I started taking a daily capsule, my test results have shown a decrease. I appreciate the dark capsules, as they maintain quality better.
6
Immune system boost
Curcumin is known for its anti-inflammatory and antioxidant effects, effectively lowering high cholesterol. Following the instructions leads to noticeable results, significantly enhancing immune function compared to Vitamin C, though it is somewhat pricey.
9
Knee pain relief
2 people found this helpful
I purchased this for my mother to normalise her cholesterol levels and reduce inflammation. It has significantly helped, as her knee pain has diminished and her elbow bruise has also improved.
7.5
Excellent quality
1 people found this helpful
I ordered this for the second time due to its excellent quality, ingredients, and packaging. It is high in antioxidants and helps reduce inflammation in the body, including conditions like arthritis.
7.5
Inflammation reduction
1 people found this helpful
I recommend this form of curcumin, as it has high bioavailability. During usage, I experienced noticeable reductions in inflammation and joint pain, which also helps during colds. The quality is excellent, and the natural ingredients are a plus.
9
Heart health improvement
1 people found this helpful
My natural health physician advises that turmeric is remarkable for its anti-inflammatory properties. It can lower high cholesterol and improve heart health. This product is easily absorbed and has become a crucial supplement for my husband and me.
7.5
Cholesterol and clots
A good antioxidant with an anti-inflammatory effect, curcumin lowers cholesterol levels and helps prevent blood clots.
8
Curcumin aids cholesterol management
An Umbrella Review of Systematic Reviews and Meta-analyses of Randomized Controlled Trials Investigating the Effect of Curcumin Supplementation on Lipid Profiles.
We explored the effects of curcumin, the active compound in turmeric, on cholesterol levels through an umbrella review of systematic reviews and meta-analyses focused on randomized controlled trials. Our objective was to assess whether curcumin supplementation could positively affect lipid profiles, particularly in relation to cholesterol levels.
In our analysis, we reviewed 26 systematic reviews, which encompassed a total of 72 randomized controlled trials. These studies compared curcumin supplementation to a placebo and measured various cholesterol components, including total cholesterol, low-density lipoprotein (LDL), high-density lipoprotein (HDL), and triglycerides.
Our findings indicate that curcumin does indeed exhibit an anti-lipidemic effect, especially beneficial for individuals with noncommunicable diseases. However, we noted that to achieve the best results, a curcumin formulation with enhanced bioavailability is recommended, ideally taken for at least eight weeks alongside regular exercise.
This approach presents a practical way to potentially lower the risk of atherosclerotic cardiovascular disease (ASCVD) while incorporating a natural supplement into our health routine.
8
Turmeric improves cholesterol levels
Effects of curcumin/turmeric supplementation on lipid profile: A GRADE-assessed systematic review and dose-response meta-analysis of randomized controlled trials.
We aimed to understand how turmeric, specifically its active compound curcumin, affects cholesterol levels in the body. After searching several online databases and analyzing 64 randomized clinical trials, we found that turmeric supplementation can lead to noticeable improvements in key cholesterol metrics.
Specifically, we observed significant reductions in total cholesterol, triglycerides, and low-density lipoprotein cholesterol (often referred to as "bad" cholesterol). Additionally, there was an increase in high-density lipoprotein cholesterol, known as "good" cholesterol. However, it's important to note that turmeric did not show considerable effects on related apolipoproteins, which are proteins that help carry cholesterol in the blood.
Although these results are promising, we must approach them with caution. The quality of evidence was assessed to be low and very low regarding these outcomes. This means that while turmeric supplementation does seem to help with certain cholesterol levels, more rigorous studies are needed to confirm these benefits and properly evaluate the overall efficacy.
8
Curcumin lowers cholesterol in PCOS
Impacts of Curcumin Supplementation on Cardiometabolic Risk Factors in Patients With Polycystic Ovary Syndrome: A Systematic Review and Dose-Response Meta-Analysis.
We explored the potential effects of curcumin, a compound derived from turmeric, on cholesterol levels and other cardiometabolic risk factors in women diagnosed with polycystic ovary syndrome (PCOS). The research included a systematic review and dose-response meta-analysis of several randomized clinical trials.
Our findings showed that curcumin supplementation significantly lowered total cholesterol levels, along with improvements in fasting blood sugar and insulin resistance. This indicates that curcumin may play a beneficial role in managing cardiometabolic health, particularly for women facing the challenges of PCOS.
However, it’s important to note that curcumin did not significantly influence body mass index, body weight, or other hormones such as testosterone and luteinizing hormone. Despite its positive effects on cholesterol, curcumin’s impact on high cholesterol remains intertwined with various factors linked to PCOS.
7
Curcumin impacts cholesterol levels
Curcumin inhibits pancreatic steatosis in mice with a high-fat diet through the YAP/p53 pathway and confirmed through ultrasonic imaging.
In our exploration of how curcumin impacts cholesterol levels, we carried out a study with male mice divided into three groups. One group received a normal diet, while another was fed a high-fat diet to induce pancreatic steatosis. The third group, however, was given curcumin in addition to the high-fat diet for 12 weeks.
We observed that those mice on the high-fat diet had significantly higher body weights and levels of cholesterol compared to the normal diet group. Yet, the addition of curcumin led to a notable reduction in inflammation and insulin resistance among the mice on the high-fat diet. This suggests that curcumin might play a role in managing cholesterol levels by modulating fat accumulation in the pancreas.
When we analyzed tissue samples, we found changes in key proteins related to lipid metabolism, indicating curcumin could influence cholesterol synthesis and regulation. Ultrasound imaging also helped us track the condition of the pancreas, showing the different fat levels in each group. Our findings point to curcumin's potential benefits for overall metabolic health, particularly in the context of high cholesterol.
9
Curcumin-piperine lowers cholesterol levels
The effects of curcumin-piperine supplementation on inflammatory, oxidative stress and metabolic indices in patients with ischemic stroke in the rehabilitation phase: a randomized controlled trial.
We conducted a study to evaluate how a combination of curcumin and piperine affects high cholesterol levels in patients recovering from ischemic stroke. Our approach involved a randomized controlled trial with 66 participants, where half received curcumin-piperine tablets while the other half got placebo tablets over 12 weeks.
Throughout the trial, we measured various health indicators including cholesterol levels, inflammatory markers, and overall well-being. Upon analyzing the results, we noticed that those who took curcumin-piperine experienced significant reductions in total cholesterol and triglycerides compared to the placebo group.
Additionally, the participants taking the curcumin-piperine supplement also showed improvements in other areas like blood pressure and carotid intima-media thickness. However, it’s essential to note that the supplement appeared beneficial within this specific population but was part of a combination treatment. Overall, we found promising effects that suggest turmeric, through curcumin and piperine, may play a role in managing high cholesterol levels associated with ischemic stroke rehabilitation.
9
Turmeric improves cholesterol levels
Synergistic Effects of Turmeric, Strawberry and Broccoli in Improving Lipid Profile in Adult Patients with Hypercholesterolemia.
We explored the effects of turmeric combined with strawberries and broccoli on cholesterol levels in adults facing hypercholesterolemia. The study involved twenty participants who consumed 600 mg of turmeric daily, along with 100 grams each of fresh strawberries and boiled broccoli for a month.
At the beginning of the study, we measured various health indicators, including cholesterol levels. For total cholesterol, we observed a decrease from 239.75 mg/dL to 220.7 mg/dL, which is statistically significant. Similarly, LDL cholesterol, known as the "bad" cholesterol, dropped from 172.9 mg/dL to 153.95 mg/dL, and triglycerides saw a decline from 193.7 mg/dL to 145 mg/dL after the treatment. However, while HDL cholesterol, often referred to as the "good" cholesterol, decreased slightly, we still found it meaningful that the overall lipid profile improved significantly with this combination of foods.
Beyond cholesterol, other blood parameters remained normal throughout the study, suggesting the treatment was safe and well-tolerated. In summary, incorporating turmeric, strawberries, and broccoli into the diet appears beneficial for lowering cholesterol levels, contributing to healthier lipid profiles for those with hypercholesterolemia.
9
Curcumin improves cholesterol levels
The Effect of Curcumin on Reducing Atherogenic Risks in Obese Patients with Type 2 Diabetes: A Randomized Controlled Trial.
We conducted a randomized, double-blind, placebo-controlled trial to understand how curcumin, a compound found in turmeric, might help in reducing high cholesterol levels in obese patients with type 2 diabetes.
Our study included 227 participants and focused on various key measurements, such as pulse wave velocity and cholesterol levels, specifically looking at low-density lipoprotein (LDL) cholesterol, known for its connection to heart health.
Over a 12-month period, those who took curcumin showed significant improvements. We noticed a remarkable reduction in pulse wave velocity, which is crucial for assessing cardiovascular risk. Additionally, levels of harmful LDL cholesterol and other cardiometabolic markers were also significantly lower in the curcumin group.
These positive findings suggest that turmeric’s active ingredient, curcumin, could be an effective natural option for managing atherogenic risks, particularly in individuals battling both obesity and diabetes.
9
Turmeric lowers inflammatory markers
The Potential Systemic Anti-Inflammatory Effect of Turmeric Dried Extract.
We analyzed the effects of turmeric on high cholesterol by conducting a study involving 30 patients. Half of the participants received a traditional fat-soluble Curcumin extract paired with piperine, while the other half took a water-soluble form known as Curcuin. Both groups were monitored for their levels of inflammation and cholesterol over a period of 90 days.
After this duration, we observed that both turmeric extracts led to a reduction in key inflammatory markers like Erythrocyte Sedimentation Rate (ESR) and C-reactive protein (CRP), as well as a decrease in cholesterol levels. Participants consuming the water-soluble Curcuin showed even more significant improvements compared to those taking the traditional extract.
Our findings suggest that turmeric may be a valuable addition to dietary strategies aimed at managing inflammation and lowering cholesterol levels. However, we also noted that the group taking the fat-soluble Curcumin combined with piperine exhibited beneficial effects, raising questions about dosage forms and frequencies for optimal results. Further studies are required to fine-tune these parameters and better understand how best to use turmeric for health benefits.
References
Unhapipatpong C, Julanon N, Shantavasinkul PC, Polruang N, Numthavaj P, et al. An Umbrella Review of Systematic Reviews and Meta-analyses of Randomized Controlled Trials Investigating the Effect of Curcumin Supplementation on Lipid Profiles. Nutr Rev. 2025. doi:10.1093/nutrit/nuaf012
Mohammadi S, Ziaei S, Morvaridi M, Hasani M, Mirtaheri E, et al. Impacts of Curcumin Supplementation on Cardiometabolic Risk Factors in Patients With Polycystic Ovary Syndrome: A Systematic Review and Dose-Response Meta-Analysis. Health Sci Rep. 2025;8:e70525. doi:10.1002/hsr2.70525
Ke H, Xu Z, Han L, Wang H, Lyu G, et al. Curcumin inhibits pancreatic steatosis in mice with a high-fat diet through the YAP/p53 pathway and confirmed through ultrasonic imaging. Biochim Biophys Acta Mol Cell Biol Lipids. 2025;1870:159605. doi:10.1016/j.bbalip.2025.159605
Montanino C, Farinella F, De Felice B, Del Buono A, D'Orta A. The Potential Systemic Anti-Inflammatory Effect of Turmeric Dried Extract. Endocr Metab Immune Disord Drug Targets. 2025. doi:10.2174/0118715303329562241116045410
Jasaputra DK, Rahardjo TM, Gunadi JW, Stefani S, Sutrisno II. Synergistic Effects of Turmeric, Strawberry and Broccoli in Improving Lipid Profile in Adult Patients with Hypercholesterolemia. Pak J Biol Sci. 2024;27:587. doi:10.3923/pjbs.2024.587.593
Lagumdžija D, Hamzić Mehmedbašić A, Jesenković DA, Kudić B, Kapić D, et al. Curcumin and its combination with a reduced dose of rosuvastatin: A promising therapy for chronic kidney disease and associated dyslipidemia in rat animal models. Biomol Biomed. 2024. doi:10.17305/bb.2024.11091
Yaikwawong M, Jansarikit L, Jirawatnotai S, Chuengsamarn S. The Effect of Curcumin on Reducing Atherogenic Risks in Obese Patients with Type 2 Diabetes: A Randomized Controlled Trial. Nutrients. 2024;16. doi:10.3390/nu16152441
Li Q, Hao Z, Xu H, Wang X. Investigation on the lipid-lowering effect and mechanism by combining turmeric with hawthorn in C57BL/6 obese mice. J Food Sci. 2024;89:4493. doi:10.1111/1750-3841.17123
Wang H, Chen L, Zhang R, Zhang G, Liu J, et al. Curcuma wenyujin rhizomes extract ameliorates lipid accumulation. Fitoterapia. 2024;175:105957. doi:10.1016/j.fitote.2024.105957
Huang Y, Liu FY, Yang JT, Zhao Q, Zhu MQ, et al. Curcumin nicotinate increases LDL cholesterol uptake in hepatocytes through IDOL/LDL-R pathway regulation. Eur J Pharmacol. 2024;966:176352. doi:10.1016/j.ejphar.2024.176352
Boshagh K, Khorvash F, Sahebkar A, Majeed M, Bahreini N, et al. The effects of curcumin-piperine supplementation on inflammatory, oxidative stress and metabolic indices in patients with ischemic stroke in the rehabilitation phase: a randomized controlled trial. Nutr J. 2023;22:69. doi:10.1186/s12937-023-00905-1
Yang J, Zou J, Mai H, Hong T, Liu H, et al. Curcumin protects against high-fat diet-induced nonalcoholic simple fatty liver by inhibiting intestinal and hepatic NPC1L1 expression via down-regulation of SREBP-2/HNF1α pathway in hamsters. J Nutr Biochem. 2023;119:109403. doi:10.1016/j.jnutbio.2023.109403
He C, Miyazawa T, Abe C, Ueno T, Suzuki M, et al. Hypolipidemic and Anti-Inflammatory Effects of -Derived Bisacurone in High-Fat Diet-Fed Mice. Int J Mol Sci. 2023;24. doi:10.3390/ijms24119366
Dehzad MJ, Ghalandari H, Amini MR, Askarpour M. Effects of curcumin/turmeric supplementation on lipid profile: A GRADE-assessed systematic review and dose-response meta-analysis of randomized controlled trials. Complement Ther Med. 2023;75:102955. doi:10.1016/j.ctim.2023.102955